- Yoo In Soo memulai debut aktingnya di tahun 2017 melalui drama yang berjudul Forgotten.
- Yoo In Soo mengaku kesal dengan Yoo Chan Young saat interview virtual All of Us Are Dead karena Chan Young melepas stiker nama dan karakternya.
- Yoo In Soo selalu menempelkan stiker namanya pada lawan mainnya.
- Selain All of Us Are Dead, beberapa drama yang dibintanginya, yaitu Strong Woman Do Bong-Soon (2017), School 2017 (2017), While You Were Sleeping (2017), Avengers Social Club (2017), Life (2018) My ID Is Gangnam Beauty (2018) Mama Fairy and the Woodcutter (2018), Drama Special Season 9: The Long Goodbye (2018), At Eighteen (2019) Love Alarm (2019), Chocolate (2019), Stranger 2 (2020), At a Distance, Spring Is Green (2021), Flying Butterflies (2021).***